Omega-3 fatty acids and inflammation in normal weight and obese subjects

niversity Hospitals Southampton NHS Fiundation Trust (UK)0 个研究点目标入组 100 人开始时间: 2012年9月5日最近更新: 2023年2月27日

适应症

试验速览

2016 Results article in http://www.ncbi.nlm.nih.gov/pubmed/27305954 Effects on lysophospholipid metabolism 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35958557/ Obesity-associated tissue remodelling (added 15/08/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35247847/ (added 16/02/2023)

•1. Male or female
•2. Aged 18 to 65 years
•3. Body mass index 18.5 to 25 or 30 to 40 kg/m2
•4. If body mass index is 30 to 40 kg/m2 waist circumference is > 94 cm for men or > 80 cm for women
•5. Not consuming fish oil or other oil supplements
•6. Not eating more than one oily fish meal per week
•7. Willing to adhere to the study protocol
•8. Being able to provide written informed consent

•1. Aged < 18 or > 65 years
•2. Body mass index < 18.5, 25-29.9 or > 40 kg/m2
•3. If body mass index is 30 to 40 kg/m2 waist circumference is < 94 cm for men or < 80 cm for women
•4. Diagnosed diabetes
•5. Use of prescribed medicine to control inflammation
•6. Use of prescribed medication to control blood lipids (e.g. statins, fibrates (fenofibrate), Omacor)
•7. Use of prescribed medication to control blood pressure (ACE inhibitors, angiotensin 2 receptor blockers, calcium channel blockers, ?Ñ-inhibitors, thiozide diuretics)
•8. Use of fish oil or other oil supplements
•9. Chronic gastrointestinal problems (e.g. IBD, celiac disease, cancer)
•10. Pregnant or planning to become pregnant within the study period
•11. Participation in another clinical trial

发起方

niversity Hospitals Southampton NHS Fiundation Trust (UK)