跳至主要内容
临床试验/NCT06689449
NCT06689449进行中(未招募)不适用

Comparison Effects of Erector Spinae Plan Block(ESP), Paravertebral Block(PVB) and Mid-point Transverse Process to Pleura Block(MTP) on Perioperative Pain Measured With Analgesia Nociceptive Index Monitor on Video-assisted Thoracoscopic Surgey(VATS)

TC Erciyes University1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年11月20日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
90
试验地点
1
主要终点
Effective analgesia control in patients with Analgesia Nociception Index(ANI)

研究概览

简要总结

In this study, our iş to compare effect of erector spinae plan block(ESP), paravertebral block(PVB) and mid-point transverse process to pleura block(MTP) on perioperative pain measured with analgesia nociceptive index monitor on video-assisted thoracoscopic surgery.

详细描述

Video-assisted thoracoscopic surgery (VATS) is a minimally invasive thoracic surgery procedure performed with the help of a retractor-free camera through small skin incisions used to diagnose and treat chest diseases. Many of the major procedures traditionally performed with open thoracoscopic surgery can be performed using smaller sections with video assistance.

Thanks to the advances in minimally invasive techniques, the non-intubated thoracoscopic approach has been adapted even for use with major lung resections.

An adequate analgesia obtained from regional anaesthesia techniques allows VATS to be performed in sedated patients and the potential adverse effects related to general anaesthesia and selective ventilation can be avoided. The non-intubated procedures try to minimize the adverse effects of tracheal intubation and general anaesthesia, such as intubation-related airway trauma, ventilation-induced lung injury, residual neuromuscular blockade, and postoperative nausea and vomiting.

Local anaesthetic techniques essential for nonentubeted video assisted thoracic surgery include thoracic epidural anaesthesia, cervical epidural anaesthesia, paravertebral block, intercostal nerve block, injection of local anaesthetic at the site of trocar incision local vagus blockade, erector spinae plane block, serratus anterior plane block and pectoralis nerve block.

Thoracic epidural analgesia, once considered the gold standard for thoracotomy; due to the risks of complications related to dural puncture, epidural hematoma, neuropathy and hypotension, it is no longer the first choice for VATS and has been replaced by peripheral blocks.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patient over the age of 18 under the 80 Who will undergo video assisted thoracic surgery -ASA group 2-3-
  • Patients without opioid addiction.
  • Patients without allergies.
  • Patients without psychiatric disorder.
  • Patients without arrhymia and beta-blocker use.
  • Patients without contraindications for peripheral blocks.

排除标准

  • Patients under age of 18
  • Patients undergo surgery under general anesthesia
  • Patients undergo emergency surgery
  • Patients allergic to local anesthesia
  • Patients wit bleeding diathesis

结局指标

主要结局

Effective analgesia control in patients with Analgesia Nociception Index(ANI)

时间窗: intraoperative

With Analgesia Nociception Index (ANI), it is advantageous to evaluate the objective findings measuring parasympathetic system activity. ANI is a monitor that can be measured continuously and non-invasively. It measures parasympathetic tone - based on electrocardiography - by analyzing minimal changes in heart rate that occur under anesthesia, in the early stages of awakening, and in each respiratory cycle of awake patients. A value between 0-100 is obtained, Values between 50 and 70 indicate good analgesia control. According to studies on ANI, the patient feels pain below 50. If it is above 70, it means that more analgesia is provided. It is thought that pain control will be more effective with these objective data.

次要结局

  • Visual analog scale(ıntraoperative and postoperative 24 hour)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Recep Aksu

clinical Professor.Recep AKSU

TC Erciyes University

研究点 (1)

Loading locations...

相似试验

Comparison Effects of Three Regional Anesthetic... | 临床试验