To see the postoperative analgesic effect of transdermal buprenorphine patch applied preoperatively in major abdominal surgeries
Not Applicable
- Conditions
- Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified
- Registration Number
- CTRI/2021/01/030441
- Lead Sponsor
- Dr Aanal Vyas
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
a total of 66 patients belonging to ASA grade 1-3,aged between 18 to 70 years, of either gender posted for major abdominal surgery under general anaesthesia with incision extending upto epigastrium were included.
Exclusion Criteria
History of allergy to study drug
• History of excessive alcohol intake/ alcohol dependence syndrome
• Pre existing cardiac diseases, uncontrolled hypertension, diabetes mellitus
• Severe asthma, chronic obstructive pulmonary diseases
• Hepatic and renal dysfunction
• A chronic pain syndrome
• Regular use of opiates, pain medications
• Pregnant or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate post operative analgesic effect of buprenorphine patch applied preoperatively before 12 hr and 24 hours on the basis of VAS score, time of first rescue analgesia, and total number of doses.Timepoint: From patch application till 72 hours postoperatively.
- Secondary Outcome Measures
Name Time Method Haemodynamic variables <br/ ><br>â?¢ Sedation score <br/ ><br>â?¢ Quality of recovery score <br/ ><br>â?¢ Adverse effect of study drugTimepoint: Preoperatively before 12/24 hrs, intraoperatively, and postoperatively till 72 hours.