Comparative Evaluation of Efficacy of Probiotics and Tetracycline Fibres as a Local Drug Delivery in the Treatment of Chronic Periodontitis Patients- A Split Mouth Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Recording Plaque index, Sulcular Bleeding Index, Pocket probing depth
研究概览
简要总结
Informed consent is obtained from the participating patients. Patients are assessed for Plaque index, Sulcular Bleeding Index and Pocket probing depth for baseline data. Following the recordings of clinical parameters, scaling and root planing will be performed. Each site will be allocated randomly into two groups i.e. Group I and Group II. Later Group I will receive Scaling and root planing followed by placement of Probiotics and placement of Coe Pak after completion of procedure. Group II will receive Scaling and root planing followed by placement of Tetracycline fibers and placement of Coe Pak after completion of procedure. The clinical parameters will be recorded again after 45 days.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group between 18 – 50 years Known cases of Chronic Periodontitis having more than 20 teeth.
- •Systemically healthy patients with no known allergy.
- •Patients who have not received periodontal or antibiotic therapy for the past 6 months.
排除标准
- •Subjects with known hypersensitivity to Tetracycline &/or Probiotics.
- •Teeth with furcation involvement.
- •Patients having habit of smoking, alcohol consumption.
- •Sites with overhanging restorations.
- •Tooth with periapical disease.
- •Subjects with orthodontic and prosthodontic appliances.
结局指标
主要结局
Recording Plaque index, Sulcular Bleeding Index, Pocket probing depth
时间窗: 0-45 days
次要结局
- Clinical Attachment Level(Baseline, 10 days & 45 days)
研究者
Anant Mishra
Army college of dental sciences Secunderabad