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Promotion and Application of a New Three-level Etiological Diagnosis Strategy for Fever Clinics in Respiratory Infectious Diseases

Recruiting
Conditions
Respiratory Infectious Diseases
Registration Number
NCT05965128
Lead Sponsor
Huashan Hospital
Brief Summary

Relying on fever clinics, this project evaluates the clinical diagnostic efficiency of the three-level pathogen diagnostic system, monitors changes in respiratory pathogens, and realizes real-time monitoring and early warning of acute respiratory infectious diseases in Shanghai.

Detailed Description

This study mainly includes subjects who enter the outpatient and emergency departments, fever clinics, and wards of each center from December 2022. According to the clinical manifestations and epidemiological information of the patients, different step-by-step detection methods will be adopted to optimize the allocation of clinical resources and improve the quality of life. This study aims to improve pathogen diagnosis efficiency and achieve regional respiratory early warning.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
1255
Inclusion Criteria
  1. Acute onset within one week;
  2. 18-70 years old;
  3. Present with pneumonia (present with pulmonary signs or radiological changes) or influenza-like illness (including the following symptoms: sudden onset of fever (>38 ℃),plus cough and/or other respiratory symptoms such as shortness of breath plus one or more systemic symptoms (fatigue, headache ect.))
Exclusion Criteria
  1. Unable to collect nasal/nasopharyngeal swab/wash/aspirate due to structural disorder or mental problem.
  2. Patients with psycological problem or unconsciousness who cannot tell the disease history and cooperate with medical examinations;

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
the detectioin rate of pathogenic microorganism in each step48 hours

the detectioin rate of pathogenic microorganism in each step

Secondary Outcome Measures
NameTimeMethod
rate of critical illness48 hours

rate of critical illness

hospitalization rate48 hours

hospitalization rate

Trial Locations

Locations (12)

Affiliated Hospital of Xuzhou Medical University

🇨🇳

Xuzhou, Jiangsu, China

Shenyang Sixth People's Hospital

🇨🇳

Shenyang, Liaoning, China

People's Hospital of Inner Mongolia Autonomous Region

🇨🇳

Hohhot, Inner Mongolia, China

The First Affiliated Hospital of Suzhou University

🇨🇳

Suzhou, Jiangsu, China

Gansu Provincial People's Hospital

🇨🇳

Lanzhou, Gansu, China

Heilongjiang Provincial Hospital

🇨🇳

Harbin, Heilongjinag, China

Shandong University Qilu Hospital

🇨🇳

Jinan, Shandong, China

The First Hospital of Shanxi Medical University

🇨🇳

Taiyuan, Shanxi, China

Fudan University Affiliated Huashan Hospital

🇨🇳

Shanghai, Shanghai, China

Jining Public Health Center

🇨🇳

Jining, Shandong, China

The First People's Hospital of Yunnan Province

🇨🇳

Kunming, Yunnan, China

Ruian City People's Hospital

🇨🇳

Rui'an, Zhejiang, China

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