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Clinical Trials/NCT03788395
NCT03788395
Completed
Phase 4

The Use of an Innovative Device for Therapeutic Adherence in Pediatric Asthma

Istituto per la Ricerca e l'Innovazione Biomedica1 site in 1 country18 target enrollmentJanuary 10, 2019

Overview

Phase
Phase 4
Intervention
Symbicort Turbohaler plus Turbo+
Conditions
Asthma
Sponsor
Istituto per la Ricerca e l'Innovazione Biomedica
Enrollment
18
Locations
1
Primary Endpoint
Medication Adherence Rating Scale (MARS)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The management of chronic diseases requires a constant monitoring of treatment adherence, in order to obtain an optimal disease control. However, this is often difficult to achieve, especially in pediatric age.

In this sense, for asthmatic patients treated by Symbicort Turbohaler, "AstraZeneca" developed the "Turbo+", an electronic device attached to the Turbohaler, which allows to feel whether the patient does the inhalation, and to register it on a specific application.

The present randomized trial aims to compare the treatment adherence between asthmatic children/adolescents aged 6-17 years treated with Symbicort Turbohaler plus Turbo+ or Symbicort Turbohaler without Turbo+.

Registry
clinicaltrials.gov
Start Date
January 10, 2019
End Date
January 23, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Istituto per la Ricerca e l'Innovazione Biomedica
Responsible Party
Principal Investigator
Principal Investigator

Stefania La Grutta, MD

Coordinator of the group "Clinical and Environmental Epidemiology of Pulmonary and Allergic Pediatric Diseases". Institute of Biomedicine and Molecular Immunology, IBIM, National Research Council of Palermo, Italy.

Istituto per la Ricerca e l'Innovazione Biomedica

Eligibility Criteria

Inclusion Criteria

  • uncontrolled mild or moderate persistent asthma;

Exclusion Criteria

  • acute upper respiratory infections;
  • immunological or metabolic systemic disease;
  • major malformations of the upper airways;
  • active smokers.

Arms & Interventions

Symbicort Turbohaler plus Turbo+

10 asthmatic children

Intervention: Symbicort Turbohaler plus Turbo+

Symbicort Turbohaler without Turbo+

10 asthmatic children

Intervention: Symbicort Turbohaler without Turbo+

Outcomes

Primary Outcomes

Medication Adherence Rating Scale (MARS)

Time Frame: 3 months

Change in the MARS score from baseline to the end of treatment

Secondary Outcomes

  • Childhood Asthma Control Test (C-ACT)(3 months)
  • Asthma Control Test (ACT)(3 months)
  • Pediatric Asthma Quality of Life Questionnaire (PAQLQ)(3 months)

Study Sites (1)

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