Biological Biomarkers in MOMS Partnership
- Conditions
- Psychological Stress
- Registration Number
- NCT02438514
- Lead Sponsor
- Yale University
- Brief Summary
The investigators propose to evaluate the potential utility of stress-related biomarkers obtained via dried blood spots (DBS) and retinal scans by collecting new data from mothers and children within the New Haven MOMS Partnership, a well-established community-partnered research setting. The proposed research could greatly advance the application of stress-related biomarkers within community-based research by increasing our understanding of how stress, trauma, and depression influence biology in childhood and adulthood, as measured using minimally-invasive approaches.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- Female
- Target Recruitment
- 20
- English-speaking adult mothers (age 21 or older) of at least one biological child mothers must be able to answer three verification questions to confirm they are the biological parent of their child
- Non-english speakers
- Women not able to provide informed consent and with no biological children
- Mothers under the age of 21
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Telomere Length At baseline-After 90 minutes Telomere length will be measured using an adapted method of the Cawthon Telomere Assay
Number of Mother-Child Dyads Who Complete Assessments & Biological Samples End of study (approximately 5 years) Feasibility outcome
Advanced Glycation End Products (AGEs) At baseline-After 90 minutes AGEs or (advanced glycation endproducts) will be measured using a painless non- invasive retinal scanning device that measures autofluorescence of the crystalline lens of the eye
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Yale University
🇺🇸New Haven, Connecticut, United States