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临床试验/CTRI/2026/01/100975
CTRI/2026/01/100975尚未招募4 期

A Dose Response Study To Evaluate The Minimal Effective Dose Of 0.5% Isobaric Levo Bupivacaine In Continuous Spinal Anaesthesia For Elective Lower Limb Surgeries

PCMC PGI YCM Hospital1 个研究点 分布在 1 个国家目标入组 67 人开始时间: 2026年2月10日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
67
试验地点
1

研究概览

简要总结

This is a prospective single centre interventional dose response study designed to evaluate the minimal effective dose of 0.5 percent isobaric levobupivacaine for continuous spinal anaesthesia in patients undergoing elective intertrochanteric femur surgery.Adult patients scheduled for surgery under continuous spinal anaesthesia will be enrolled.0.5 percent Isobaric Levobupivacaine will be administered intrathecally through a spinal catheter in incremental doses as per the study protocol. The primary objective is to determine the minimal effective dose required to achieve adequate surgical anaesthesia. Secondary objectives include assessment of hemodynamic changes and onset and duration of sensory and motor block and total number of top ups required and incidence of adverse effects during the intraoperative and immediate postoperative period.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Elective intertrochanteric femur surgery .
  • Height 150cm-180cm.

排除标准

  • Allergy to local anaesthetics .
  • Coagulopathy or anticoagulant therapy .
  • Infection at puncture site.

研究者

发起方
PCMC PGI YCM Hospital
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr.Mitali Khobragade

PCMC PGI YCM Hospital, Pimpri , Pune

研究点 (1)

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