Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.

Completed

• Conditions: Supraventricular Arrhythmias
• Interventions: Other: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias

• Registration Number: NCT03665324
• Lead Sponsor: Rennes University Hospital

Brief Summary

Supraventricular arrhythmias (including atrial fibrillation) are the most common arrhythmias of the veteran athlete and have a major impact in terms of morbidity and mortality. Although moderate sports practice has been shown to decrease the occurrence of these arrhythmias, it has also been shown that very intense athletic activity is associated with an increased risk of developing atrial fibrillation. The pathophysiological mechanism is not clearly understood. However, it has already been shown that intensive sports practice leads to electrical and morphological atrial remodeling, which could be the cause of the occurrence of supraventricular arrhythmias for these athletes.

For sedentary patients, two major tools predict the risk of the onset of supraventricular arrhythmia: the electrocardiogram (ECG) and transthoracic echocardiography (ETT), particularly with the study of atrial function by the analysis of myocardial deformities.

Detailed Description

No studies have tested these two tools for the evaluation of atrial remodeling of the veteran athlete to predict which ones are at risk of developing supraventricular arrhythmias.

However, the identification of predictive factors would make it possible to identify at-risk athletes and thus provide them with adapted sporting practice advice and personalized follow-up.

The aim of the study is to evaluate the relationship between atrial remodeling assessed by ECG and ETT with the occurrence of supraventricular arrhythmia by comparing an athlete group with supraventricular arrhythmia with a control group of healthy athletes.

Study Timeline

• Study Start: 2017-04-28
• Primary Completion: 2017-05-15
• Study Completion: 2017-05-15
• Status Verified: 2018-09
• Study First Submitted: 2018-09-05
• Study First Submitted QC: 2018-09-07
• Last Update Submitted: 2018-09-07
• Study First Posted: 2018-09-11
• Last Update Posted: 2018-09-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Supraventricular arrhythmia group : Veteran athletes with documented paroxysmal supraventricular arrhythmias.
• Control Group : Veteran athletes without documented supraventricular arrhythmia.

Exclusion Criteria

• Any cardiopathy (valvulopathy, coronary heart disease, etc.).
• Minor patients,
• Major patients subject to legal protection (legal safeguards, guardianship)
• Persons deprived of their liberty
• Patients opposed to the use of their personal data.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Veteran athletes without supraventricular arrhythmia	Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias	Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) without documented supraventricular arrhythmia.
Veteran athletes with Supraventricular arrhythmias	Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias	Subjects who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017 Veteran athletes (age\> 35 years) with documented paroxysmal supraventricular arrhythmias.

Primary Outcome Measures

Name	Time	Method
Study of atrial function by analysis of myocardial strain.	At the inclusion day	Myocardial strain in extracted from ETT and compared between the two groups.

Trial Locations

Locations (1)

Rennes University Hospital; 🇫🇷 Rennes, France