To studt the effect of three different doses of a drug named dexmedetomidine on irregular jerky movements of body induced by etomidate induced myoclonus
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047551
- Lead Sponsor
- Department of Anaesthesia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients belonging to American Society of Anaesthesiologist Grade I and II, posted for elective surgery under general anaesthesia
Exclusion Criteria
Patient refusal
Patient with known allergy to study drug
Patients with history of recent myocardial infarction ( <3 months), uncontolled hypertension, bradycardia, heart blocks, heart failure
patients with epilepsy, hepatic failure, psychiatric disease, sepsis or systemic infections, neurological disease
patients with major illnesses like bronchial asthma, chronic cough, upper respiratory tract infection 2 weeks prior to surgery
patients who had received analgesics or sedatives within previous 24 hours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare the incidence and severity of etomidate induced myoclonus in all 3 groupsTimepoint: after induction with etomidate for 3 minutes
- Secondary Outcome Measures
Name Time Method 1.To study and compare the incidence of adverse effects of dexmedetomidine <br/ ><br>2.To study and compare the effect of different doses of dexmedetomidine on attenuation of stress response to laryngoscopy and intubationTimepoint: 1. from onset of action of dexmedetomidine to injection of etomidate <br/ ><br>2. before starting dexmedetomidine infusion till 5 minutes after intubation