A Randomized Controlled Trial Comparing the Segmental Artery Clamping and Main Renal Artery Clamping During Laparoscopic Partial Nephrectomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Kidney Neoplasms
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Glomerular Filtration Rate
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to compare the efficacy and safety of the segmental artery clamping and main renal artery clamping during laparoscopic partial nephrectomy
Detailed Description
Renal tumor patients,for whom laparoscopic partial nephrectomy is suitable, will be randomly divided into two groups,segmental artery clamping group and main artery clamping group. All procedures were performed by the same laparoscopic surgeon. Blood loss, operation time, warm ischemia time, complications and affected renal function before and after operation will be recorded and compared. The safety and efficiency of laparoscopic partial nephrectomy with segmental renal artery clamping will be evaluated in comparison with the conventional main renal artery clamping technique.
Investigators
Changjun Yin
Head of Urology Department
The First Affiliated Hospital with Nanjing Medical University
Eligibility Criteria
Inclusion Criteria
- •20\<age\<70yr
- •Stage T1a
- •Patients volunteered for this study and provided written informed consent
Exclusion Criteria
- •Bilateral renal tumor
- •tumor of solitary kidney
- •glomerulonephritis
- •renal insufficiency
- •GFR of invalid kidney less than 30ml/min
- •presence of suspect metastasis
- •serious systematic disease: severe coagulation disorders
- •important organ insufficiency and severe psychological disease
Outcomes
Primary Outcomes
Glomerular Filtration Rate
Time Frame: 3 months postoperative
Secondary Outcomes
- warm ischemia time(during surgery)