The Vitamin D and Psoriasis Study

Recruiting

• Conditions: Psoriasis vulgaris; Skin - Dermatological conditions; Diet and Nutrition - Other diet and nutrition disorders; Human Genetics and Inherited Disorders - Other human genetics and inherited disorders

• Registration Number: ACTRN12611000648921
• Lead Sponsor: Massey University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-06-24
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Medically diagnosed psoriasis vulgaris

Exclusion Criteria

Smoking; chronic kidney or liver disease; currently taking vitamin D supplements, or have taken them within the past two months; pregnant or lactating, or planning to be in the near future; have commenced a new psoriasis treatment within the past three months and wish to continue

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in Psoriasis Area and Severity Index (PASI) scores in treatment group compared to placebo group.[Baseline, 3 months, 6 months, 9 months and 12 months.];Change in serum 25(OH)D levels and PASI scores according to different vitamin D receptor genetic polymorphisms.[Baseline, 3 months, 6 months, 9 months and 12 months.]

Secondary Outcome Measures

Name	Time	Method
Quality of life as assessed using the Dermatology Life Quality Index questionnaire.[Baseline, 3 months, 6 months, 9 months and 12 months.];Change in inflammatory marker levels in the treatment group compared to the placebo group.[Baseline, 3 months, 6 months, 9 months and 12 months.]