Pectoral Nerves I, II and Serratus Plane Blocks in Multimodal Analgesia for Mastectomies A Randomized Clinical Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Regional Anesthesia
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- Change in Pain score over 24 hours
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Acute postoperative pain is a common problem faced by the patient after surgery, most frequently occurring in first 24 hours. Our primary objective was to assess pain score in first 24 hours in PECS block group undergoing mastectomies. Secondary objective was to observe morphine (opioids) and antiemetic consumption in post anesthetic care unit.
Detailed Description
Design: Observer Blinded Randomized control trial. Place and Duration: Department of Anesthesiology, Shaukat Khanum Memorial Cancer Hospital Lahore (SKMCH), from February 2017 to December 2017 Methods: 120 patients more than 18 years, ASA I and II, planned for unilateral elective modified radical mastectomy under general anesthesia were randomly assigned to receive either general anesthesia plus Pectoral Nerve I, II and serratus (PECS) block (n = 60) or general anesthesia alone (n = 60). Pain score at fixed intervals was measured using Numeric Pain Rating Score (NPRS) after surgery.
Investigators
Hammad Najeeb
Fellow in Anesthesia
Shaukat Khanum Memorial Cancer Hospital & Research Centre
Eligibility Criteria
Inclusion Criteria
- •Female age 18 or older
- •(ASA) I and II
- •Scheduled to undergo elective unilateral mastectomy or Modified radical mastectomy (MRM) under general anesthesia.
Exclusion Criteria
- •Patient's refusal
- •history of allergy to bupivacaine
- •contraindications to regional anaesthesia (coagulopathy and local infection),
- •BMI \> 40 kg/m2,
- •patient scheduled for bilateral mastectomies
- •use of chronic pain medications
- •history of illicit drugs or alcohol abuse and history of psychiatric problems.
Outcomes
Primary Outcomes
Change in Pain score over 24 hours
Time Frame: First 24 hrs
Patient's pain intensity was assessed using NPRS (Numeric Pain scoring system). Pain score was assessed at the time of arrival at PACU (0 minute) and then at 30 minutes after surgery and at discharge from PACU. Pain score was then assessed at the surgical floor at 6hours, 12hours and 24hours.
Secondary Outcomes
- Post operative morphine (opioids) consumption in PACU(first 24 hours)
- Antiemetic consumption for treatment of PONV(120 minutes)