跳至主要内容
临床试验/NCT06080308
NCT06080308招募中不适用

Research on the Molecular Mechanisms of Liver Ischemia-reperfusion Injury and Clinical Data Analysis: an Observational Study

Qin Zhang1 个研究点 分布在 1 个国家目标入组 270 人开始时间: 2023年10月10日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
270
试验地点
1
主要终点
Length of hospital stay

研究概览

简要总结

Searching for new targets for the diagnosis and treatment of liver ischemia-reperfusion injury.

详细描述

Through the analysis of serological data during liver resection elective surgery with hepatic pedicle occlusion and reperfusion, as well as the analysis of patient-related data, we aim to identify key target points that affect reperfusion injury and explore their underlying mechanisms.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Willingness to participate in the study and has signed an informed consent form. 2) Age ≥ 18 years and ≤ 70 years. 3) ASA classification ≤ III. 4) Criteria for liver ischemia-reperfusion injury patients: patients undergoing elective liver resection surgery with hepatic pedicle occlusion and reperfusion during the procedure.

排除标准

  • Patients with adverse events during surgery. 2) Patients in the end stage of disease with liver failure. 3) Liver tumor metastasis with concomitant severe heart failure or chronic renal insufficiency, etc. 4) Deemed unsuitable for participation in the study based on the judgment of the researchers.

结局指标

主要结局

Length of hospital stay

时间窗: 7days

Length of hospital stay

次要结局

未报告次要终点

研究者

发起方
Qin Zhang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Qin Zhang

phd

Tongji Hospital

研究点 (1)

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