Mapping of brain tau deposition in tauopathy by PET with [18F]PM-PBB3

Not Applicable

Recruiting

• Conditions: mild cognitive impairment, Alzheimer' s disease, corticobasal degeneration, progressive supranuclear palsy, frontotemporal degeneration, Parkinson' s disease, Lewy body dementia,Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex Patients in Kii Peninsula, Diffuse neurofibrillary tangles with calcification, hereditary diffuse leukoencephalopathy with spheroid,Progressive Ataxia and Palatal Tremor, traumatic brain injury

• Registration Number: JPRN-UMIN000030248
• Lead Sponsor: ational Institute of Radiological Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-01
• Study Completion: 2021-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Not provided

Exclusion Criteria

1) Subjects with neurodegenerative disease 1. Subjects with organic brain complications/disorders 2.Subjects with substance-related disorders 3.Subjects with severe physical complications/disorders or a history of such conditions 4. Subjects with claustrophobia 5. Pregnant, possibly pregnant or lactating women 6. From the standpoint of radiation exposure from a nuclear medicine scan, subjects who have participated in other nuclear medicine scans as healthy volunteers in the 6 months prior to the start of this study 7. Subjects who are considered to be inappropriate for participation by doctors with responsibilities in this study 2) Subjects with traumatic brain injury 1. Subjects with any organic brain disorder not due to traumatic brain injury 2. Subjects with severe physical complications/disorders or a history of such conditions 3. Subjects with claustrophobia 4. Pregnant, possibly pregnant or lactating women 5. From the standpoint of radiation exposure from a nuclear medicine scan, subjects who have participated in other nuclear medicine scans as healthy volunteers in the 6 months prior to the start of this study 6. Subjects who are considered to be inappropriate for participation by doctors with responsibilities in this study 3) Healthy volunteers 1. Subjects with organic brain complications/disorders 2. Subjects with substance-related disorders 3.Subjects with severe physical complications/disorders or a history of such conditions 4. Subjects with claustrophobia 5. Pregnant, possibly pregnant or lactating women 6. From the standpoint of radiation exposure from a nuclear medicine scan, subjects who have participated in other nuclear medicine scans as healthy volunteers in the 6 months prior to the start of this study 7. Subjects who are considered to be inappropriate for participation by doctors with responsibilities in this study 8. Subjects with tattoo 9. Subjects with metallic medical device in the body

Study & Design

• Study Type: Interventional
• Study Design: Not specified