Comparison of efficacy of topical clobetasol 0.05% plus 5FU 5% cream vs. topical clobetasol 0.05% alone in the treatment of vitiligo.
- Conditions
- Vitiligo.vitiligo
- Registration Number
- IRCT201203049198N2
- Lead Sponsor
- Isfahan Univercity of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 45
Inclusion criteria were as follow: vitiligo patients with at least 2 lesions on the body, >15 years old, lack of follicular pigmentation (score=0), lack of white hair over the lesion and disease stability within the last 6 months.
Exclusion criteria were as follow: those who had recieved topical medication for at least 1 month and systemic medication or phototherapy for at least 3 months prior to inclusion; past medical history of liver, kidney and hematologic disorders; the vitiligo lesions on the face, genitalia or acral areas; pregnancy or lactation and the segmental subtype. Patients were instructed about the study protocol, possible side effects and a written informed consent was taken from all patients before enrollment.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method esion of vitiligo. Timepoint: End of three months. Method of measurement: Pigmentation score.
- Secondary Outcome Measures
Name Time Method Erythema,atrophy,erosion. Timepoint: any time during treatmrnt. Method of measurement: observation.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.