Bone Mineral Density in Pediatric Epilepsy
Completed
- Conditions
- Epilepsy
- Registration Number
- NCT00204815
- Lead Sponsor
- University of Wisconsin, Madison
- Brief Summary
What are the effects of the currently used AEDs on bone mineralization in children and adolescents between the ages of 8 to 18? This is a pilot observational study using DEXA scans to measure bone mineral density in 100 patients The primary objective is to collect preliminary data on bone mineral density, body weight, dietary calcium intake, and activity level.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 98
Inclusion Criteria
- diagnosis of generalized or partial seizures with or without generalization or a diagnosis of generalized seizures as defined in the International League Against Epilepsy
Exclusion Criteria
- steroid use
- chronic disease other than epilepsy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie AED-induced bone mineral density changes in pediatric epilepsy (NCT00204815)?
How do AEDs like valproic acid and lamotrigine differentially affect bone mineral density in children with epilepsy?
Which biomarkers predict AED-related changes in bone mineral density among pediatric epilepsy patients?
What adverse events are associated with AEDs on bone health in pediatric epilepsy and how are they managed?
Are combination therapies of AEDs with bisphosphonates beneficial for bone mineral density in pediatric epilepsy patients?
Trial Locations
- Locations (1)
University of Wisconsin Hospital and Clinics
🇺🇸Madison, Wisconsin, United States
University of Wisconsin Hospital and Clinics🇺🇸Madison, Wisconsin, United States