ACT: Avastin and Chemotherapy followed by Avastin alone or in combination with Tarceva for the treatment of metastatic colorectal cancer - ACT
- Conditions
- Patients with previously untreated metastatic colorectal carcinoma
- Registration Number
- EUCTR2006-002295-18-DK
- Lead Sponsor
- niversity Hospital, Dept of Oncology, clinical trial unit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 182
Untreated metastatic colorectal carcinoma
Age = 18 years
Measurable disease according to Response Evaluation Criteria in solid Tumors (RECIST) criteria
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Life expectancy more than 3 months
Adequate haematological, renal and liver function
Blood sample and paraffin embedded tumour tissue for translational research
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Adjuvant therapy within 6 months
Central nervous system (CNS) metastases
Clinically significant atherosclerotic vascular disease
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method