Evaluation of the efficacy of yokukansan for postoperative delirium
Not Applicable
- Conditions
- postoperative delirium
- Registration Number
- JPRN-UMIN000027976
- Lead Sponsor
- Tottori University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with past history of hypersensitivity to yokukansan or anchusan Patients diagnosed with pseudoaldosteronism Patients diagnosed with heart failure Patients with a history of rhabdomyolysis Patients diagnosed with interstitial pneumonia Patients diagnosed with liver failure Patients who cannot start oral administration early after surgery, such as esophageal cancer patients Patients with mood disorder, schizophrenia, schizoaffective disorder, alcoholism, drug addiction Patients determined to be unable to join the clinical trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence rate of delirium diagnosed using DSM-5 by psychiatrists on postoperative day 1,2, and 3
- Secondary Outcome Measures
Name Time Method Severity of delirium by Delirium Rating Scale R-98 Safety (adverse events, laboratory values, postoperative complications, postoperative mortality)