Extended Hip Ultrasound as Anew Protocol for Septic Hip in Children

Not yet recruiting

• Conditions: Septic Arthritis

• Registration Number: NCT06003374
• Lead Sponsor: Assiut University

Brief Summary

To establish a new protocol in order to increase ultrasound diagnostic accuracy of pediatrics presented with signs of septic hip .

Detailed Description

Septic arthritis is a severe life and function threatening condition with a 1-year mortality rate of up to 10% and residual functional impairments in 30% to 50% of cases . Pediatric Septic Hip Arthritis is an intra-articular infection in children that peaks in the first few years of life. The incidence of septic arthritis is low, with about 4-5 per 100000 child annually with about 50% of cases occur in children younger than 2 years of age with gender affection in male \> female (2:1 ratio). The hip joint involved in about 35% of all cases of septic arthritis. Imaging studies contribute crucially to the optimal management of septic arthritis, thereby diminishing the risk of permanent functional loss .At present; magnetic resonance imaging (MRI) is the most informative method. Thus, MRI assesses the severity of the synovitis and can detect a joint effusion, bone and/or cartilage destruction, an abscess, and/or bone edema. MRI had 75% specificity and nearly 100% sensitivity for diagnosing concomitant abscess formation, cellulitis, or myositis . Disadvantages of MRI are high cost and limited availability on an emergency basis in some settings , Ultrasonography of the bone and joints has been developing at a fast pace in recent years. Ultrasonography is currently used in the management of septic arthritis to confirm the presence of a joint effusion and to guide the joint aspiration or synovial biopsy, particularly when the effusion is small or the joint deep (e.g., hip). Ultrasonography has high sensitivity and specificity for joint effusions .The difficulty of applying hip MRI in pediatric age group patients especially neonates make challenge in the proper management of acute septic hip arthritis .the study aim to apply a new protocol in diagnosis of septic hip in children by doing extended hip ultrasound included psoas and quadriceps muscles.

Study Timeline

• Study First Submitted: 2022-12-17
• Status Verified: 2023-06
• Study First Submitted QC: 2023-08-12
• Last Update Submitted: 2023-08-12
• Study First Posted: 2023-08-22
• Last Update Posted: 2023-08-22
• Study Start: 2023-09-15
• Primary Completion: 2024-12-01
• Study Completion: 2025-01-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• Neonates, infants and children presented with suspected septic hip arthritis.

Exclusion Criteria

• DDH

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To describe the ultrasound abnormalities seen in Patients with septic hip arthritis.	Baseline	To evaluate: 1. Synovial membrane thickness .; 2. Synovial membrane vascularity.; 3. Presence of a joint effusion.; 4. Presence of a joint loculation.; 5. Presence of a joint erosions.