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临床试验/NCT06003374
NCT06003374尚未招募不适用

Extended Hip Ultrasound as Anew Protocol for Septic Hip in Children

Assiut University0 个研究点目标入组 46 人开始时间: 2023年9月15日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
46
主要终点
To describe the ultrasound abnormalities seen in Patients with septic hip arthritis.

研究概览

简要总结

To establish a new protocol in order to increase ultrasound diagnostic accuracy of pediatrics presented with signs of septic hip .

详细描述

Septic arthritis is a severe life and function threatening condition with a 1-year mortality rate of up to 10% and residual functional impairments in 30% to 50% of cases . Pediatric Septic Hip Arthritis is an intra-articular infection in children that peaks in the first few years of life. The incidence of septic arthritis is low, with about 4-5 per 100000 child annually with about 50% of cases occur in children younger than 2 years of age with gender affection in male > female (2:1 ratio). The hip joint involved in about 35% of all cases of septic arthritis. Imaging studies contribute crucially to the optimal management of septic arthritis, thereby diminishing the risk of permanent functional loss .At present; magnetic resonance imaging (MRI) is the most informative method. Thus, MRI assesses the severity of the synovitis and can detect a joint effusion, bone and/or cartilage destruction, an abscess, and/or bone edema. MRI had 75% specificity and nearly 100% sensitivity for diagnosing concomitant abscess formation, cellulitis, or myositis . Disadvantages of MRI are high cost and limited availability on an emergency basis in some settings , Ultrasonography of the bone and joints has been developing at a fast pace in recent years. Ultrasonography is currently used in the management of septic arthritis to confirm the presence of a joint effusion and to guide the joint aspiration or synovial biopsy, particularly when the effusion is small or the joint deep (e.g., hip). Ultrasonography has high sensitivity and specificity for joint effusions .The difficulty of applying hip MRI in pediatric age group patients especially neonates make challenge in the proper management of acute septic hip arthritis .the study aim to apply a new protocol in diagnosis of septic hip in children by doing extended hip ultrasound included psoas and quadriceps muscles.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Week 至 15 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Neonates, infants and children presented with suspected septic hip arthritis.

排除标准

  • 未提供

结局指标

主要结局

To describe the ultrasound abnormalities seen in Patients with septic hip arthritis.

时间窗: Baseline

To evaluate: 1. Synovial membrane thickness . 2. Synovial membrane vascularity. 3. Presence of a joint effusion. 4. Presence of a joint loculation. 5. Presence of a joint erosions.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dalia Khaled Mostafa Mohamed

Resident doctor at diagnostic radiology department at assuit univerity

Assiut University

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