A STUDY TO ASSESS THE EFFECT OF AYURVEDIC TREATMENT IN THE BIOMARKER TNF-ALPHA IN PSORIASIS
- Conditions
- Psoriasis vulgaris. Ayurveda Condition: EKAKUSHTHAH,
- Registration Number
- CTRI/2020/11/028867
- Lead Sponsor
- Dr Neethi Rajan
- Brief Summary
Psoriasis is a common, chronic inflammatory recurrent cutaneous auto immune disease. Patients with Psoriasis satisfying the inclusion and exclusion criteria will be included in the trial. The objective of the trial is to do the assessment of Psoriasis using the biomarker TNF-alpha and PASI Score after applying the Ayurvedic treatment modalities. The participants will be given 3days Amapachana with Shaddharanam Choorna, Snehapana for 7days with Mahathikthaka Ghrta, Abhyanga and Ushnodaka snana for 1day and Virechana with Vellaruku taila for 7days consecutively. Assessment of biological marker will be done on the day before Amapachana (0th day), after Virechana (19th day) and on the 45th day. Assessment of PASI score will be done on the basis of scoring criteria.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 20
- External dryness 2.
- Thickness 5.
- Erythematous patches 6.
- Well demarcated plaques of skin 7.
- Auspitz sign 8.
- Those who are willing to take part in the trial.
- Other autoimmune diseases 2.
- Infectious diseases 3.
- Multiple joint pain 4.
- Chronic systemic disorders or congenital disorders 5.
- Under steroid therapy 6.
- Pregnant and lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TNF-α value Assessment of TNF-α will be done on 0th day, 19th day and on 45th day | PASI SCORE before and after treatment PASI SCORE Assessment of TNF-α will be done on 0th day, 19th day and on 45th day | PASI SCORE before and after treatment
- Secondary Outcome Measures
Name Time Method Generalised well being of the patient 45days
Trial Locations
- Locations (1)
Government Ayurveda College Panchakarma Hospital
🇮🇳Thiruvananthapuram, KERALA, India
Government Ayurveda College Panchakarma Hospital🇮🇳Thiruvananthapuram, KERALA, IndiaDr Neethi RajanPrincipal investigator9400460781neethirajan150@gmail.com