Correlation of Ama status with specific Biomarkers in Patients of Sandhigata Vata (Osteo Arthritis)
Not Applicable
- Conditions
- Health Condition 1: M150- Primary generalized (osteo)arthritisHealth Condition 2: M150- Primary generalized (osteo)arthritisHealth Condition 3: M150- Primary generalized (osteo)arthritis
- Registration Number
- CTRI/2022/11/047327
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Adult subjects of either sex between the age group of 30 to 70 years irrespective of chronicity.
2) Presence of cardinal sign and symptoms of Sandhigata vata.
3) Digital x-ray depicting the features of osteoarthritis.
4) Patients willing to incorporate themselves in the study.
Exclusion Criteria
1) Severe cases of osteoarthritis with stiffness and immobility.
2) Any other conditions of the joints and bones like Rheumatoid arthritis and Ankylosing Spondylitis, Tubercular arthritis or infective Arthritis will be excluded.
3) Any malignant condition of the body.
4) Systemic diseases like Diabetes mellitus, Hypothyroidism etc.
5) Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess status of ama in Sandhigata vata (Osteo Arthritis) along with assessment of Advanced glycation End product and Lipid peroxidation comparison with healthy individuals as control <br/ ><br>Study the relationship between the status of Ama, AGE and Lipid Peroxidation in patients of Sandhigata vata (Osteo Arthritis)Timepoint: At the time of first visit (Baseline)
- Secondary Outcome Measures
Name Time Method To explore the corelation of Advanced Glycation End product with lipid peroxidation as a marker of oxidative stress in patients of Sandhigata vata. <br/ ><br>To study the relationship between disease activity score (with WOMAC Score) and Ama in the patients of Sandhigata vata.Timepoint: At the time of first visit (Baseline)