yoga for diabetic autonomic neuropathy

Not yet recruiting

• Conditions: Other specified diabetes mellituswith neurological complications,

• Registration Number: CTRI/2021/12/039068
• Lead Sponsor: Aiims Rishikesh

Brief Summary

Yoga may also reduce activation of the sympathoadrenal system and hypothalamic-pituitary-adrenal axis, and may enhance parasympathetic activity, thereby alleviating stress. Clinical trials with both healthy and ill participants have shown the benefit of yoga on stress reduction. By supporting stress resilience, yoga may prevent stress-induced rises in cortisol, thus controlling the rise in blood glucose levels.  Pilot studies conducted mainly in India have shown decreased stress levels among diabetics after a yoga intervention.  Evidence also suggests that stress leads to poor food choices, including increased consumption of foods high in fat, sugar, and salt. By reducing stress and improving mindfulness, yoga practice may lead to improved self-care behaviors including improved diet and physical activity. Randomized trials with adults at risk for cardiovascular disease and binge eaters have shown improved dietary outcomes after a yoga intervention.  Thus, yoga may positively impact stress, diet, and other self-care tasks that contribute to improved glycaemic control.

**Aim:**

To **compare the efficacy of yoga-based intervention vs.  American Diabetes association exercise regime in addition with standard of care** **for autonomic neuropathy in type two diabetes mellitus**

 **Hypothesis**

Yogic exercises are equally effective as compared to the American Diabetes association exercise regime for improving autonomic functions in patients suffering from diabetic autonomic neuropathy

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-12-22
• Study Start: 2022-05-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Patients of Type two diabetes mellitus with diagnosed Autonomic Neuropathy. Age Between 35.

Exclusion Criteria

• Patients opting for treatment not in compliance with randomization sequence Patients on insulin Patients with HbA1c > 11%.
• Patients with acute macro vascular complications, cancer, pulmonary tuberculosis, and rheumatoid arthritis Patients who will be unable to perform yoga.
• Patients receiving drugs like drotaverine, beta-blockers or any other drug likely to affect autonomic function tests Patients with history of angina/uncontrolled hyperglycaemia/any other contraindication applied by American Diabetic Association (ADA).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
effect of Yoga based intervention on Autonomic function in Type Two Diabetes Mellitus patients suffering from Autonomic Neuropathy	baseline , 4 week, 8th week and 12th week

Secondary Outcome Measures

Name	Time	Method
Change in HbA1c, lipid profile, Nerve Conduction Velocity, Liver function test, Kidney function test, fasting blood sugar, Post prandial blood sugar, Random blood Sugar	Change in HbA1c, lipid profile, Nerve Conduction Velocity, Liver function test, Kidney function test, fasting blood sugar, Post prandial blood sugar, Random blood Sugar
Change in dose of Oral hypoglycaemic agents	4th week, 8th week and 12 week

Trial Locations

Locations (1)

aiims; 🇮🇳 Dehradun, UTTARANCHAL, India

aiims

🇮🇳Dehradun, UTTARANCHAL, India

Ramesh kumar

Principal investigator

9027300507

rks.aiimsrishikesh@gmail.com