NCT07343570Not yet recruitingPhase 3
Comparing Ultrasound-guided Lateral Quadratus Lumborum Block Versus Combined Ilio-inguinal/Ilio-hypogastric /Genitofemoral Block for Postoperative Analgesia After Open Inguinal Hernia Repair: A Double-blind Randomized Controlled Trial
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Al-Azhar University
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- Cumulative opioid consumption in the first 24 hours postoperatively
Study Overview
Brief Summary
This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block-for postoperative analgesia after elective unilateral open inguinal hernia repair under spinal anesthesia in adults.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adults aged 18-75 years.
- •ASA physical status I-III.
- •Scheduled for elective unilateral open inguinal hernia repair under standardized spinal anesthesia.
- •Able to understand and use the Visual Analogue Scale (VAS).
- •Provided written informed consent.
Exclusion Criteria
- •Allergy to local anesthetics.
- •Coagulopathy or current use of anticoagulants contraindicating peripheral nerve blocks.
- •Infection at the injection site.
- •Chronic opioid use (daily opioids >2 weeks) or chronic pain syndromes.
- •Body mass index (BMI) >40 kg/m².
- •Conversion to other surgery or bilateral repair.
- •Pregnant patients.
- •Refusal to sign informed consent.
Outcomes
Primary Outcomes
Cumulative opioid consumption in the first 24 hours postoperatively
Time Frame: 24 hours after surgery.
Measures the total amount of opioid analgesics (expressed as morphine milligram equivalents, MME) consumed during the first postoperative 24 hours. It reflects overall analgesic efficacy of the two block techniques.
Secondary Outcomes
- Pain intensity (VAS pain scores at rest )(24 hours postoperatively.)
- Pain intensity (VAS pain scores at movement)(24 hours postoperatively.)
- Time to first analgesic request(24 hours.)
- Proportion of patients requiring rescue opioid analgesia(24 hours.)
- Incidence of postoperative block-related complications(24 hours.)
- Patient satisfaction score(Assessed at 24 hours postoperatively.)
- Post-anesthesia care unit (PACU) stay duration(24 hours)
- Total hospital stay duration(24 hours)
Investigators
Neveen Abd El Maksoad Kohaf
Lecturer of Clinical Pharmacy
Al-Azhar University
Study Sites (1)
Loading locations...
Similar Trials
Recruiting
Not Applicable
Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal SurgeryNCT07326774Fatih Sultan Mehmet Training and Research Hospital60
Recruiting
Not Applicable
Retrolaminar Analgesia for LuMbar SurgeryNCT07334288Universidad de los Andes, Chile50
Recruiting
Not Applicable
EOI Block in Otoplasty With Rib Cartilage GraftNCT07262944Seoul National University Hospital60
Completed
Phase 2
A clinical study to assess postoperative analgesic effects of Quadratus lumborum block with dexmedetomidine after open inguinal herniotomy and hydrocele surgery in childreCTRI/2023/09/057338Kanishka S44
Completed
Not Applicable
This is a clinical study to know the effectiveness of quadratus lumborum block in relieving post operative pain of patients undergoing renal transplantatioCTRI/2017/06/008924Sanjay gandhi post graduate institute of medical sciences60