Blood collection to study and modulate dendritic cell-driven T cell responses

• Conditions: Autoimmunity; 10001708; allergy; met name gezonde vrijwilligers worden geincludeerd. Donoren met een allergie of auto-immuunziekte worden niet uitgesloten

• Registration Number: NL-OMON54980
• Lead Sponsor: Amsterdam UMC, locatie AMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

- age between 18 and 65 year

Exclusion Criteria

- ongoing inflammation or infection at time of blood collection
- use of immunosuppressive or biological medication within the last 6 month
prior to blood collection
- active malignancies
- subjects who are employees or students at our department

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>This is not directly applicable within our research. Important aspects that we<br /><br>investigate in vitro are:<br /><br>- T cell polarization towards Th1, Th2, Th17, and Treg phenotype.<br /><br>- DC function/activation<br /><br>- neutrophil function/activation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>