Deep Brain Stimulation for Treatment of Severe Disability From Traumatic Brain Injury
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Traumatic Brain Injury
- Sponsor
- Ali Rezai, MD
- Enrollment
- 4
- Locations
- 1
- Primary Endpoint
- Improvement in Brain Functioning
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The study will evaluate the benefit of Deep Brain Stimulation for subjects with severe disability due to Traumatic Brain Injury.
Detailed Description
The study will evaluate the benefit of Deep Brain Stimulation for subjects with severe disability due to Traumatic Brain Injury. DBS has been proven safe and efficacious for remediation of multiple neurological conditions. It is the hope of the study team that the protocol will provide further insight into the potential of DBS to improve the quality of life and functioning of persons with severe disability due to TBI and at the same time can provide new clinical insights that will improve treatment for the entire spectrum of injury severity.
Investigators
Ali Rezai, MD
MD
Ohio State University
Eligibility Criteria
Inclusion Criteria
- •24 months post traumatic brain injury Scores in Severe range of the Glasgow Outcome Scale-Extended Evidence of impaired cognitive functioning Medically and neurologically stable
Exclusion Criteria
- •Medical contraindications for surgery Evidence of substance abuse in the last 12 months Current Diagnosis of major depressive disorder current participation in rehabilitation services Co-morbid conditions that would interfere with study activities
Outcomes
Primary Outcomes
Improvement in Brain Functioning
Time Frame: 16 months
Brain functioning improvement in functional independence, community participation and subjective well-being.