A phase III international randomized trial of single versus multiple fractions for re-irradiation of painful bone metastases
- Conditions
- Painful bone metastates from any cancer after previous palliative radiotherapy.Cancer - Bone
- Registration Number
- ACTRN12607000064404
- Lead Sponsor
- ational Cancer Insitute of Canada
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 850
1. Patient must have histologically or cytologically proven malignancy. Histological diagnosis may be established from needle biopsy, bone marrow biopsy, cytology, or a surgical biopsy or resection. All malignant histologies/cytologies are eligible. 2. Plain radigraphs, radionuclide bone scans, CT scans and/or magnetic resonance imaging confirm the presence of bone metastatses corresponding to clinically painful area.
1. Clinical or radiological evidence of spinal cord compression at the time of assessment for this study.2. Clinical or radiological evidence of pathological fractures of extremities in the area to be re-irradiated.3. The treatment area has received prior palliative surgery.4. There is planned surgical intervention on the treated bone.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method