AFFIRM trial:Alterations in Faecal Flora Intrinsically Related to Metformin.
- Conditions
- Type 2 diabetes, metformin, gutmicrobiota
- Registration Number
- NL-OMON21550
- Lead Sponsor
- Academic Medical CentrePO Box 22660 1100 DD Amsterdam Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 18
Inclusion Criteria
1. Male obese subjects with an impaired fasting glucose or newly diagnosed diabetes;
2. 21-65 yr;
Exclusion Criteria
1. Renal failure;
2. Liver function problems;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in faecal flora after 15 weeks.
- Secondary Outcome Measures
Name Time Method 1. Glycemic control;<br /><br>2. Biochemical parameters;<br /><br>3. Inflammatory parameters;<br /><br>4. Weight.