Evaluation of Garlic With Lime Juice and Chlorhexidine Mouthwash on Gingival Bleeding in Group of Egyptian Children: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- gingival bleading
研究概览
简要总结
the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.
详细描述
the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque.
- Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group.
provide chlorhexidine to the second group. 2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria. 3. Asses gingival condition by asking patient. 4. Subjects will be instructed to rinse for 14 days, twice daily. 5. Morning after breakfast and night before going to bed. 6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse. 7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
This was a double-blind study as the investigator was unaware about the sampling of the groups and study subjects were unaware about the mouthwash they were using
入排标准
- 年龄范围
- 9 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
garlic with lime juice mouthwash
garlic with lime juice mouthwash is herbal antimicrobial .children were instructed to rinse for 14 days, twice daily, ,10 ml (undiluted) for 30 second and then expectorate .
To prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.
干预措施: garlic with lime mouth wash (Drug)
chlorhexidine mouthwash
chlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days. it is commercial mouthwash
.
干预措施: chlorhexidine (Drug)
结局指标
主要结局
gingival bleading
时间窗: 15 day
bleeding of gingiva asses by yes or no
次要结局
- Streptococcal count in saliva and plaque(15 day)
研究者
manal sayed abdel latief
oral and dental medicine
Cairo University