mPATH for Low-income Older Adults
- Conditions
- InsomniaCognitive DeclineSedentary Time
- Interventions
- Behavioral: mPATHOther: Attention Control
- Registration Number
- NCT05935241
- Lead Sponsor
- Johns Hopkins University
- Brief Summary
Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.
- Detailed Description
Low-income older adults (LIOA) are a population at higher risk to develop Alzheimer's disease and related dementias (ADRD) and sleep disturbances. Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in LIOA. The growing wearable device and mobile Health (mHealth) provide an innovative approach to deliver individually tailored physical activity interventions at home with flexible schedules to overcome barriers to physical activity in LIOA. In addition, limited research has examined if physical activity interventions impact the individual's Amyloid/Tau/ Neurodegeneration (ATN) Alzheimer's disease biological state and whether physical activity may promote cognition through impacting sleep and AD pathology. This randomized controlled trial is designed to examine the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in LIOA. mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 176
- self-reported difficulty of sleep
- lack of physical activity/exercise
- low household income
- capacity for moderate intensity exercise
- untreated sleep apnea
- severe depression or anxiety
- dementia
- history of neurologic or psychiatric disorders, neurodevelopmental impairment, traumatic brain injury
- current enrollment in another clinical trial
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description mPATH mPATH mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months Education and Social control Attention Control This attention control group is designed to match the intervention for mPATH's staff-subject interaction duration through monthly home visits in the first 6 months
- Primary Outcome Measures
Name Time Method Change in episodic memory as assessed by the Cogstate Alzheimer's Battery Baseline, 6 months, 12 months Episodic memory will be measured by computerized cognitive batteries using the Cogstate Alzheimer's Battery.
- Secondary Outcome Measures
Name Time Method Change in Sleep efficiency as assessed by actigraphy Baseline, 6 months, 12 months sleep efficiency will be measured by 7-day actigraph (reported as a percentage).
Trial Locations
- Locations (1)
The Johns Hopkins University, School of Nursing
🇺🇸Baltimore, Maryland, United States