Transcriptomic Evaluation of Endometrial Receptivity
Completed
- Conditions
- Infertility, Female
- Interventions
- Other: Endometrial biopsy
- Registration Number
- NCT04141085
- Lead Sponsor
- Reproductive Medicine Associates of New Jersey
- Brief Summary
The purpose of this study is to comprehensively evaluate the transcriptomic signal of the endometrium before, during, and after the window of receptivity.
- Detailed Description
Phase 1 will aim to define a normal endometrial transcriptomic signature in healthy controls without infertility. Phase 2 will elucidate endometrial transcriptomic expression in patients with diagnoses of infertility unrelated to endometrial factor. Findings from this phase will be compared to the results of phase 1.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 63
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Infertile Patients Endometrial biopsy Infertile patients with a history of infertility but without concern for endometrial dysfunction as the cause of their infertility. Healthy volunteers without infertility Endometrial biopsy Healthy volunteers without a history of infertility who have regular menstrual cycles and whom have not had any intrauterine procedures performed in the last 90 days prior to participation in the study
- Primary Outcome Measures
Name Time Method transcriptomic evaluation 90 days evaluation to characterize genes expressed during the window of implantation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Reproductive Medicine Assoicates of New Jersey
🇺🇸Basking Ridge, New Jersey, United States