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Clinical Trials/NCT05827705
NCT05827705
Completed
Not Applicable

The Effects of Position and Predictive Factors on Hypotension in Patients Undergoing Prone Percutaneous Nephrolithotomy

Bursa Yüksek İhtisas Education and Research Hospital1 site in 1 country153 target enrollmentMarch 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hypotension
Sponsor
Bursa Yüksek İhtisas Education and Research Hospital
Enrollment
153
Locations
1
Primary Endpoint
Prone position effects on hypotension
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This study was designed to investigate the effect of position and predictive factors on hypotension in patients performing percutaneous nephrolithotomy. Patients aged >18 years and ASA I-III who underwent general or regional anaesthesia were included in the study. Percutaneous access was performed in all patients with fluoroscopy in the prone position.

Detailed Description

This study was designed to investigate the effect of position and predictive factors on hypotension in patients performing percutaneous nephrolithotomy. Patients aged \>18 years and ASA I-III who underwent general or regional anaesthesia were included in the study. Percutaneous access was performed in all patients with fluoroscopy in the prone position. Age, gender, body mass index(BMI), smoking, type of anaesthesia, duration of anaesthesia and surgery were recorded. The ECG, SpO2, and non-invasive blood pressure values were recorded intraoperatively. Preoperative and postoperative 12th hour Hb,BUN, Cr,Na,K and Cl were measured in a blood sample. Isotonic was used as an intravenous fluid in all participants. In treatment of hypotension routine ephedrine treatments were recorded. In the literature, studies in PCNL surgery have focused on data such as method, duration of bleeding and fluoroscopy, electrolyte-metabolic changes, and complications such as fever, hypothermia, pleural damage, and hospital stay. A limited number of studies have focused on bleeding and hemodynamics in comparing surgical methods in the prone and supine positions. the investigators could not find any study comparing systemic disease effects on intraoperative hypotension (hemodynamic parameters) in Prone PCNL surgery.

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
April 1, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Bursa Yüksek İhtisas Education and Research Hospital
Responsible Party
Principal Investigator
Principal Investigator

Seyda Efsun Ozgunay

Asocc Prof

Bursa Yüksek İhtisas Education and Research Hospital

Eligibility Criteria

Inclusion Criteria

  • Patients aged \>18 years and ASA I -III who underwent general or regional anaesthesia were included in the study.

Exclusion Criteria

  • Patients who received preoperative vasopressor, inotropic infusion, erythrocyte and fresh frozen plasma (FFP), anaemia, uncontrolled coagulopathies, pregnancy, immunodeficiency, ASA class IV and emergency surgeries.

Outcomes

Primary Outcomes

Prone position effects on hypotension

Time Frame: Perioperative period

Systolic blood pressure (SBP) \<90 mmHg, mean arterial pressure (MAP) \<65 mmHg, or a decrease of more than 20% of baseline

1.Perioperatif hypotension and presence of systemic diseases

Time Frame: Perioperative period

Systolic blood pressure (SBP) \<90 mmHg, mean arterial pressure (MAP) \<65 mmHg, or a decrease of more than 20% of baseline

Secondary Outcomes

  • mortality(30 days after the surgery)

Study Sites (1)

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