The NAtional Trial of Tonsillectomy IN Adults: a clinical and cost effectiveness study

ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)0 个研究点目标入组 645 人开始时间: 2014年8月4日最近更新: 2024年1月22日

适应症

试验速览

2015 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/26047934 protocol 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37209706/ (added 22/05/2023) 2023 Results article in https://doi.org/10.3310/ykur3660 (added 11/01/2024)

•1. Age 16 years and over
•2. Recurrent sore throats which fulfil current SIGN guidance for elective tonsillectomy.
•3. Subject has provided written informed consent for participation in the study prior to any study specific procedures
•ENT staff for the feasibility study interviews must be ENT staff members at a participating site and likely to be involved in the proposed NATTINA trial.
•There are no exclusion criteria for GPs for the feasibility study.

•1. Under 16 years of age
•2. Previous tonsillectomy
•3. Listed directly (i.e. added to waiting list without prior elective ENT outpatient appointment) during emergency admission (e.g. due to peritonsillar abscess/quinsy)
•4. Primary sleep breathing disorder
•5. Suspected malignancy
•6. Tonsilloliths
•7. Pregnant or breastfeeding
•8. Bleeding diathesis
•9. Therapeutic anticoagulation
•10. Inability to complete self-reported questionnaires and sore throat returns
•There are no exclusion criteria for GPs or ENT staff for the feasibility study.

发起方

ewcastle upon Tyne Hospitals NHS Foundation Trust (UK)