Assessment of preload responsiveness in patients undergoing non cardiac surgery by assessing descending aortic flow through echocardiography under suprasternal window
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/05/066669
- Lead Sponsor
- Jasnoor Kaur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Elective non cardiac surgery
2.Patients of either sex
3.Age=18 years and =65 years.
4.American Society of Anaesthesiologists (ASA) I-III.
5.BMI=30kg/m2.
Exclusion Criteria
Refusing to participate in study
ASA greater than IV
Obese BMI greater than or equal to 30kg/m2
Significant cardiovascular disease
Echocardiographic views not obtainable
History of myocardial infarction
History of low Ejection fraction or poor cardiac contractility
Patients on inotrope or vasodilator infusions
Arrhythmias
Modified Allen’s test negative
Any neurosurgical case with risk of increased Intracranial Pressure with Passive Leg Raise
Patients of abdominal compartment syndrome
Pregnant female
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the thresholds of dynamic indices of respiratory variation in peak aortic flow in descending aorta(?V peak descAo)and respiratory variation in Left ventricular outflow tract (?V peak LVOT) to passive leg raise in differentiating preload responders and non-responders.Timepoint: Before and 1 minute after Passive Leg Raise (PLR)
- Secondary Outcome Measures
Name Time Method 2.Compare the percentage change in hemodynamic and echocardiography parameters Heart Rate (?HR), Systolic Blood Pressure(?SBP), Diastolic Blood Pressure (?DBP), Mean Arterial Pressure(?MAP), Stroke Volume Index(?SVI) and Cardiac Index (?CI) with PLR between responders and non-responders.Timepoint: Before and 1 minute after Passive Leg Raise (PLR);3.Compare the hemodynamic and echocardiography parameters HR, SBP, DBP, MAP, SVI, and CI between responders and non-responders.Timepoint: Before and 1 minute after Passive Leg Raise (PLR);To determine diagnostic profile, and level of agreement for percentage change in peak aortic flow in descending aorta (?V peak descAo) and in Left ventricular outflow tract (?V peak LVOT) before and after PLR, in predicting preload responsiveness to PLR among mechanically ventilated patients scheduled for non-cardiac surgeryTimepoint: Before and 1 minute after Passive Leg Raise (PLR)