Sequential Therapy versus Quadruple Therapy for H.pylori Eradication in Ira

Phase 1

• Conditions: Condition 1: Peptic ulcer. Condition 2: Gastritis.; Gastric ulcer -Duodenal ulcer - erosion (acute) of stomach -erosion (acute) of duodenum; Chronic gastritis, unspecified , Acute (erosive) gastritis with haemorrhage; K25-K26

• Registration Number: IRCT201103183836N1
• Lead Sponsor: Jundishapour Ahvaz Uuniversity of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Inclusion: Patients older than 14 years of age with dyspepsia, gastrointestinal bleeding, history of post prandial fullness and vomiting, undertake endoscopy.Two biopsies of the antrum and gastric body will perform. Those patients who have a positive rapid urease test or histological evidence for H. pylori in the gastric mucosa will enroll.
Exclusion:Patients with severe comorbidity, such as cirrhosis, kidney failure, severe heart disease, pregnancy, lactation and evidence of malignancy, a previous history of eradication of H. pylori, a history of NSAID use, alcohol consumption and H2 blocker or PPI in the past two weeks or who haVE receive antibiotics and bismuth subcitrate in the last month will be excluded.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Eeradication helicobacter pylori. Timepoint: Four weeks. Method of measurement: Urea breath test.

Secondary Outcome Measures

Name	Time	Method
Side effect. Timepoint: Three days. Method of measurement: Good, intermediate and poor assessed by physician.