Topiramate for tobacco dependence

Not Applicable

Completed

• Conditions: Tobacco dependence, major depressive disorder; Mental and Behavioural Disorders; Tobacco dependence

• Registration Number: ISRCTN93532081
• Lead Sponsor: The Carlos III Health Institute (Instituto de Salud Carlos III) (Spain)

Brief Summary

2008 results in: https://www.ncbi.nlm.nih.gov/pubmed/18462502 (added 31/05/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-02-27
• Study Completion: 2009-12-31
• Last Update Posted: 26 June 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

1. Patients aged 18 - 65 years, either sex
2. Able to understand and read Spanish
3. Fulfill criteria for major depression (Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV] criteria)
4. Scores on the Zung Self-Rating Depression Scale less than 60 (implying minimal to mild depression)
5. Smoke more than 20 cigarettes/day
6. Fulfil preparation state of change according to Prochaska and DiClemente classification
7. Voluntarily ask for a tobacco cessation therapy
8. Sign informed consent

Exclusion Criteria

1. Active psychosis and/or treatment with antipsychotic drugs
2. Alcohol or drug abuse
3. Pregnancy or lactation

Study & Design

• Study Type: Interventional
• Study Design: Not specified