Effect of Clomiphene Citrate on Uterine Hemodynamics in Women With Unexplained Infertility
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Flow index of the endometrial region
研究概览
简要总结
In a prospective observational study at a university teaching hospital, blood flow indices and serum hormone levels were compared between spontaneous and stimulated cycles in the same group of 50 patients with unexplained delayed conception.
详细描述
In a prospective observational study at a university teaching hospital, the mid-luteal (peri-implantation) endometrial thickness and volume, uterine artery pulsatility index (PI) and resistance index (RI), endometrial and subendometrial vascularization index, flow index, and vascularization flow index, and serum estradiol and progesterone levels were compared between spontaneous and clomiphene citrate stimulated cycles in the same group of 50 patients with unexplained infertility.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Unexplained infertility
- •Body mass index less than 30
- •Regular menstruation
- •Normal pelvic examination and ultrasonography
排除标准
- •History of pelvic operations including cesarean section
- •History of pelvic inflammatory disease
- •Endometriosis
- •Pelvic pathology including uterine fibroids
- •General disease or medication that could potentially affect pelvic blood flow
结局指标
主要结局
Flow index of the endometrial region
时间窗: Day 22 to 24 of the menstrual cycle
Flow index of the endometrial region was measured by a researcher
次要结局
- Vascularization index of the endometrial region(Day 22 to 24 of the menstrual cycle)
- Vascularization flow index of the endometrial region(Day 22 to 24 of the menstrual cycle)
- Vascularization index of the sub-endometrial region(Day 22 to 24 of the menstrual cycle)
- Flow index of the sub-endometrial region(Day 22 to 24 of the menstrual cycle)
- Vascularization flow index of the sub-endometrial region(Day 22 to 24 of the menstrual cycle)
研究者
Eman Omran
principal investigator
Cairo University