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Insulin and protein in critically ill children.

Conditions
Critically Ill septic Children admitted to the PIC
Registration Number
NL-OMON29492
Lead Sponsor
ErasmusMC - Sophia Children's Hospital
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

Children admitted to the Pediatric Intensive Care Unit:

1. Diagnosis of SIRS, sepsis or septic shock, as determined by the criteria of the First International pediatric sepsis forum (Pediatric Critical Care Medicine 2005 vol 6 page 3-8);

Exclusion Criteria

1. Patients with metabolic diseases i.e.: urea cycle disorders, cystinuria and insulin dependent diabetes mellitus;

2. Patients with hepatic or renal failure;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
WHole body Protein Balance.
Secondary Outcome Measures
NameTimeMethod
1. Insulin resistance;<br /><br>2. Glucose metabolism;<br /><br>3. Lipolysis and Glycerol metabolism.
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