Evaluation of a Multidisciplinary Care Pathway on the Evolution of Renal Function in Patients With Advanced Chronic Kidney Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Kidney Function Issue
- Sponsor
- Association d' Utilisation du Rein Artificiel SANTE
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Glomerular filtration rate
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
The number of incident and prevalent patients with end stage renal disease on dialysis treatment is increasing in France and worldwide. A quarter of dialysis patients are initiating dialysis urgently through central venous catheters and the number of patients registered in the waiting list for renal transplantation before dialysis initiation is very low. This is also reflected in the very low number of pre-emptive renal transplantations.
In order to reduce the number of dialysis patients, the French state has induced a national program proposing a multidisciplinary care pathway including the nephrology visits and at least one consultation with a dietitian and a specialist renal nurse in all patients with Chronic Kidney Disease stage 4 and 5.
The aim of this single-center retrospective study is to evaluate the influence of the complete, partial or no participation in this program on the evolution of renal function and clinicobiological parameters in this group of patients.
Investigators
PAGES Helene
Principal Investigator
Association d' Utilisation du Rein Artificiel SANTE
Eligibility Criteria
Inclusion Criteria
- •All stage 4 and 5 Chronic Kidney Disease patients that were included in the program from 01/01/2021 to 31/12/2021 in the clinics of AURA SANTE
Exclusion Criteria
- •Patients without a medical follow up during this year (2021)
- •Patients with insufficient or no data during the 24 month of follow up period
- •Active treatment with corticosteroids, cytotoxic or immunosuppressive drugs, ongoing infection, autoimmune disease or active tumor process
Outcomes
Primary Outcomes
Glomerular filtration rate
Time Frame: Every 6 months for 24 months
The estimated Glomerular filtration rate is estimated with the CKD-EPI formula adjusted for 1.73m2 of body surface area and produced in ml/min/1.73m2 of body surface area
Secondary Outcomes
- Patients survival rate(Every 6 months for 24 months)
- Renal survival rate(Every 6 months for 24 months)
- Haemoglobin levels(Every 6 months for 24 months)
- Plasma Calcium levels(Every 6 months for 24 months)
- Plasma alcaline reserve levels(Every 6 months for 24 months)
- 24h salt consumption(Every 6 months for 24 months)
- Plasma Phosphate levels(Every 6 months for 24 months)
- Plasma parathyroid hormone levels(Every 6 months for 24 months)
- 24h protein consumption(Every 6 months for 24 months)
- Quality of life score(through study completion, an average of 6 months)