Study of Blood Platelets in Sickle Cell Disease
Withdrawn
- Conditions
- Sickle Cell Disease
- Registration Number
- NCT00226083
- Lead Sponsor
- Rockefeller University
- Brief Summary
We are studying if sickle cell disease blood platelets are larger than normal and how they may cause obstruction of blood vessels. We are also trying to study the reasons why large platelets are found in patients with sickle cell disease.
- Detailed Description
Research volunteers are seen in the Outpatient Research Center by the Principal Investigator or another physician. A detailed history is obtained, a physical examination is performed, and blood (usually 4 tablespoons) is obtained for additional tests. The research volunteer's previous medical records will be requested. Upto 5 additional blood samples may be obtained in a subgroup of patients.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Adults and children > 7 years of age with sickle cell disease (Hb SS) who are not taking hydroxyurea and are not receiving routine blood transfusion therapy.
Exclusion Criteria
- Current hydroxyurea therapy or,
- Hydroxyurea use within the past 3 months
- Blood transfusion or exchange transfusion within the past 3 months
- Current treatment with aspirin or clopidogrel
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Rockefeller University Hospital
🇺🇸New York, New York, United States