NCT00226083WithdrawnNot Applicable
Studies of Large Platelets in Patients With Sickle Cell Disease
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Sponsor
- Rockefeller University
- Locations
- 1
Study Overview
Brief Summary
We are studying if sickle cell disease blood platelets are larger than normal and how they may cause obstruction of blood vessels. We are also trying to study the reasons why large platelets are found in patients with sickle cell disease.
Detailed Description
Research volunteers are seen in the Outpatient Research Center by the Principal Investigator or another physician. A detailed history is obtained, a physical examination is performed, and blood (usually 4 tablespoons) is obtained for additional tests. The research volunteer's previous medical records will be requested. Upto 5 additional blood samples may be obtained in a subgroup of patients.
Study Design
- Study Type
- Observational
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 7 Years to — (Child, Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Adults and children > 7 years of age with sickle cell disease (Hb SS) who are not taking hydroxyurea and are not receiving routine blood transfusion therapy.
Exclusion Criteria
- •Current hydroxyurea therapy or,
- •Hydroxyurea use within the past 3 months
- •Blood transfusion or exchange transfusion within the past 3 months
- •Current treatment with aspirin or clopidogrel
Investigators
Study Sites (1)
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