Detection of Chlamydia trachomatis antibodies in vaginal swabs as an intermediate marker for PID and tubal pathology * pilot study
Withdrawn
- Conditions
- ChlamydiaPIDtubal infertility1000855510013356
- Registration Number
- NL-OMON36428
- Lead Sponsor
- RIVM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
In STI-clinics: women who tested positive or negative in a PCR test for (current) genital Chlamydia trachomatis infection and are willing to participate in the study.
In fertility clinic: women who tested positive or negative with serum Chlamydia antibody test (CAT).
Exclusion Criteria
In STI clinics: women with coinfection HIV, girls under 18 years old.
In infertility clinic: women with HIV.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To compare the presence and quantity/titres of IgG antibodies findings with the<br /><br>health status of the patients regarding current (vaginal) Chlamydia infections,<br /><br>history of prior Chlamydia infections, in lower genital tract (vagina, cervix)<br /><br>or higher parts (pelvic, ovaria: PID) and fertility-related problems (tubal<br /><br>pathology).</p><br>
- Secondary Outcome Measures
Name Time Method <p>Depending on the outcomes of this pilot, we aim to set-up a larger study to<br /><br>investigate the prevalence of these antibodies in vaginal samples and the risk<br /><br>for PID prospectively in a dual cohort of women, screened and unscreened.</p><br>