comparison between suction aspiration technique and combination technique of simultaneous use of aspiration catheter and retrieval stents in large artery occlusion required for intra-arterial recanalization therapy

Not Applicable

Conditions: Diseases of the circulatory system

Registration Number: KCT0007726

Lead Sponsor: Inje University Haeundae Paik Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: All

Target Recruitment: 1132

Inclusion Criteria

acute cerebral infarction with initial NIHSS = 4
-patients with agreement for clinical trials
-detection of large artery occlusion based on CT or MR angiography
-definition of large artery occlusion: 1) anterior circulation
ICA, M1, M2 segment
A1, A2 segment
2)posterior circulation
Vertebrobasilar occlusion including P1 segment
-Last normal time = 24 hours
-Flow/volume mismatch = 1/2 based on perfusion image

Exclusion Criteria

-Previous disabled patients before MT (Karnofsky performance Status Scale(KPS) = 80)
-Patient or patient’s guardian refused to the clinical trial
-Small vessel disease of TOAST classification
-Other determined etiologies of TOAST classification
-Patients with Initial NIHSS = 3
-Diffusion/perfusion matched lesion or flow/volume matched lesion

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
comparison of clinical outcome 3 months after IAT between between suction aspiration and combination techniques in M2 occlusions;comparison of clinical outcome 3 months after IAT between rescue treatment of primary stenting and sequential treatment in large artery atherosclerotic steno-occlusion;10.comparison of radiological outcome between more than 1/2 based on flow/volume of CT perfusion and calculated volume of mismatch based on flow/volume of CT perfusion;15.comparison of clinical outcome 3 months after IAT between hot-line prehospital tele-communication and conventional group;comparison of clinical outcome using modified Rankin Scale (mRS) 3 months after IAT between suction aspiration and combination techniques;comparison of clinical outcome using mRS 3 months after IAT between suction aspiration and combination techniques;comparison of clinical outcome using mRS 3 months after IAT between between combination technique using 6mm sized stents and the others techniques in M1 occlusion

Secondary Outcome Measures