Assessment of fracture healing by high-resolution peripheral quantitative computer tomography (HRpQCT) and bone strength analysis in standard care and after immediate administration of vitamin D. - Fracture healing by HRpQCT in standard care and after vitamin D.

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 52 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

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•1.Postmenopausal women older than 50 years who present themselves in clinic with a distal radius fracture due to a trauma. 2.2. Patients with any non-operative stable distal radius fracture that is treated by cast immobilization. 3.Patients who understand the conditions of the study and are willing and able to comply with the scheduled biochemical and radiographic evaluations. 4.Patients who signed the Ethics Committee approved specific Informed Consent Form prior to inclusion.

•1.Patients who underwent surgery of the wrist or radius on a previous occasion on the same side or who need surgery this time. 2.Patients with active or suspected infection such as pneumonia or complicated urinary tract infection in the last 3 months. 3.Patients with malignancy in the last 12 months. 4.The patient with a neuromuscular or neurosensory deficit which would limit the ability to assess the performance during the healing period. 5.Patients with known systemic or metabolic disorders leading to progressive bone deterioration: hyperthyroidism, hyperparathyroidism, chronic kidney disease with eGFR<30 ml/min 6.Patients with an active inflammatory disease during the last year such as reumatoid arthritis, SLE, inflammatory bowel disease (M. Crohn and colitis ulcerosa) 7.The prolonged use of oral glucocorticoids during the last 6 months 8.Patients, who as judged by the principal Investigator, are mentally incompetent or are unlikely to be compliant with the follow-up evaluation schedule. 9.Patients with other severe concurrent joint involvements which can affect their outcome. 10.Patients who are already selected for another trial concerning distal radius fractures.

发起方

Medisch Universitair Ziekenhuis Maastricht