Retrospective Study of Efficacy and Safety of the Endoscopic Removal of Cancerous and Precancerous Lesions of the Upper and Lower Digestive Tract
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endoscopic Mucosal Resection
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
- Enrollment
- 2000
- Locations
- 1
- Primary Endpoint
- recurrence rate
- Status
- Recruiting
- Last Updated
- 7 months ago
Overview
Brief Summary
The study aims to retrospectively investigate the endoscopic resection procedures of cancerous and precancerous lesions of the upper and lower digestive tract in order to evaluate the efficacy and safety outcomes and to compare different resection techniques. In particular, the resection techniques investigated will be mucosectomy, en bloc and piecemeal, endoscopic submucosal dissection (ESD) and its variants, full-thickness resection. The anatomical districts involved will be the esophagus, stomach, duodenum, colon and rectum.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 years or older
- •all patients who have undergone endoscopic resection of an upper or lower digestive tract tumor
Exclusion Criteria
- •age under 18
- •inability to provide informed consent
Outcomes
Primary Outcomes
recurrence rate
Time Frame: one year
recurrence is the recurrence of the neoplasm at the resection site during follow-up
complete resection rate
Time Frame: one month
the complete resection is the ability to remove the neoplasia with clear margins (R0)
en bloc resection rate
Time Frame: one month
the en bloc resection is the ability to remove the neoplasia in a single piece
Secondary Outcomes
- adverse events rate(one month)
- costs(one month)