Genetic Analysis of Pediatric Psoriasis

Northwestern University1 site in 1 country86 target enrollmentOctober 17, 2018

ConditionsPsoriasis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Psoriasis
Sponsor: Northwestern University
Enrollment: 86
Locations: 1
Primary Endpoint: CARD14 mutations
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study will ascertain approximately 150 subjects, which will include pediatric psoriasis patients diagnosed before age 12, parents not affected by psoriasis, and if a family history is indicated, up to third-degree family members. Saliva (or buccal swabs in the case of infants) will be obtained for DNA isolation.

Registry

clinicaltrials.gov

Start Date

October 17, 2018

End Date

December 30, 2021

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Northwestern University

Responsible Party

Principal Investigator

Amy Paller

Principal Investigator

Northwestern University

Eligibility Criteria

Inclusion Criteria

•Patients (of any age) who developed psoriasis before 12 years of age and who have no family history of psoriasis in either parent.
•Parents of patients who developed psoriasis before 12 years of age
•Up to third-degree family members (first cousin, grandparent, great-grandparent) with or without psoriasis, if family history is indicated.

Exclusion Criteria

•Patients, parents, and other family member unable to give a saliva or buccal swab sample.
•Patients, parents, and other family member unable to give written informed consent.