Comparative evaluation of Bone Mineral Density and Primary Implant Stability with Sandwich Technique using Perioglass and Platelet Rich Fibrin with or without Laser Assisted Socket Preservation: A Randomized Controlled Clinical and Radiographical Trial

Krizaj et al. (2020)10 performed  a study to evaluate a comprehensive laser post-extraction protocol by comparing results of alveolar bone regeneration with standard extraction procedure alone versus when added with laser therapy. 53 simple extractions were randomized to either laser or control group. In the laser group, erbium (Er:YAG; 2940 nm) and neodymium (Nd: YAG; 1064 nm) lasers were used for degranulation, disinfection, de-epithelialization of the surrounding gingiva, clot stabilization and photobiomodulation. The primary outcome measure was change in bone density in the extraction area between day 1 and 4 months after extraction. The study concluded that the proposed laser post-extraction procedure is a safe and effective method to improve post-extraction bone healing.

Monea et al. (2015)11 conducted a study to determine whether low level laser therapy (LLLT) can decrease the time between extraction/socket graft and implant placement, by evaluating histological changes in sockets grafted with a particulate allograft material and treated with LLLT. Thirty patients had a socket grafted with a particulate allograft material (MinerOss) covered with a resorbable collagen wound dressing. The patients were then randomly divided into two equal groups (n = 15): test group receiving postoperative LLLT treatment, and control group without postoperative laser treatment. The assessment of bone formation was carried out in both groups at well-determined time intervals after surgery by histomorphometric analysis. The study concluded that LLLT photobiomodulation reduces the healing time after grafting the extraction socket. Histological evidence suggested that new bone formation in the sockets appeared within 60 days after LLLT treatment compared to a minimum of 120 days in the control group.