EXIST: Physical exercise to improve fitness and combat fatigue in patients with Multiple Myeloma or (non-) Hodgkin*s lymphoma after high dose chemotherapy and autologous stem cell transplantation. - EXIST

Academisch Medisch Centrum0 sites125 target enrollmentTBD

Overview

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

last year

Study Type

Interventional

Sponsor

•\-diagnosed with multiple myeloma in first line or or with HL/NHL in first line or first relapse, who have undergone HDC and autologous SCT 6 to 12 weeks ago or who where recently (\< 8 months) treated with HDC and autologous SCT and who have completed radiotherapy or their last cycle of consolidation chemotherapy 2 to 6 weeks ago\-Sufficiently recovered from the SCT and having peripheral blood recovery;
•\-Age between 18 and 65 years;
•\-Ability to cycle on a bicycle ergometer against a load of at least 25 Watt;
•\-Ability to walk at least 100 meters independently without crutches/cains or walking frame;
•\-Written informed consent.

•\-tandem autologous\-allogeneic stem cell transplantation
•\-Severe cognitive impairment;
•\-Severe emotional instability;
•\-Insufficient mastery of the Dutch language;
•\-Presence of extensive osteolytic lesions with risk of fracture;
•\-Serious cardiopulmonary and cardiovascular conditions;
•\-Other disabling comorbidity interfering with the intervention program or influencing outcome parameters (a.o. having a pacemaker , epileptic seizures and poorly regulated diabetes mellitus);
•\-Severe infections;
•\-Relapse/progression of disease.