跳至主要内容
临床试验/CTRI/2023/12/060893
CTRI/2023/12/060893已完成不适用

Effect of Elemental Processing and Levels of Recollection for Recognition Memory on the Experience of Anhedonia in Persons with Depressive Disorders

Deepak Sunilkumar Sharma1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2024年1月2日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
105
试验地点
1
主要终点
HAM-D score as a measure of severity of depression

研究概览

简要总结

Individuals with depressive disorder did not differ significantly from healthy participants in terms of information processing style or recognition of episodic memory. The processing style and patterns of recollection of recognition memory did not have any significant relationship with the experience of anhedonia in individuals with depressive disorder. The present study did not find any effect of information processing style and patterns of recollection of recognition memory on the experience of anhedonia in individuals with depressive disorder, unlike previous studies conducted on individuals with schizophrenia. It may indicate the possibility that the presentation and cognitive correlates of anhedonia in the two psychiatric conditions may be different, despite the transdiagnostic nature of anhedonia.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Diagnosis: Major Depressive Episode with active symptoms, individuals with depressive disorder in remission (A score of less than 7 on Hamilton Depression Rating Scale), and healthy individuals (no diagnosis) Education: Class 6 or higher.

排除标准

  • Individuals with a history of head injury, organic brain syndrome, symptoms suggestive of seizures, intellectual disability or any severe physical illness.
  • Individuals with severe depression, active suicidal ideation, or any severe comorbid psychopathology, including psychotic symptoms, Obsessive Compulsive Disorder, Bipolar Depression, Substance Intoxication, Dependence or Withdrawal, and Severe Personality Psychopathology.

结局指标

主要结局

HAM-D score as a measure of severity of depression

时间窗: Single [Cross-sectional study]

Anhedonia score on SHAPS-C as a measure of anhedonia

时间窗: Single [Cross-sectional study]

Performances (% correct responses) on biconditional discrimination task and simple discrimination task as measures of processing styles

时间窗: Single [Cross-sectional study]

Performance (% correct response) on Remember-Know task as a measure of recognition memory recollection

时间窗: Single [Cross-sectional study]

次要结局

未报告次要终点

研究者

发起方
Deepak Sunilkumar Sharma
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Deepak Sunilkumar Sharma

Lokopriya Gopinath Bordoloi Regional Institute of Mental Health, Tezpur

研究点 (1)

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