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临床试验/CTRI/2026/02/103524
CTRI/2026/02/103524尚未招募2 期

A randomised clinical comparative study of bhunimba sharkara vati and bilvamajja vati in the management of garbhini chardi in first trimester with special reference to emesis gravidarum.

Vd Veena Ramesh Kelamangalath1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年2月20日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
To compare the effect of Bhunimba Sharkara vati and Bilvamajja vati in the management of garbhini chardi in first trimester w.s.r. to emesis gravidarum

研究概览

简要总结

Pregnancy is delicate with many physical and hormonal changes in woman as the growing fetus depends entirely on the mother. Women are considered as one of the most essential factor for continuity of race.Pregnancy though a natural process,can have complications at any stage due to changes in a pregnant woman’s body anatomy and physiology.So during these nine months of pregnancy ,a woman has to undergo a number of physical, emotional, physiological changes which alter her day to day activities. One of these changes is Garbhini Chardi.

This symptom remains severe for first three to four months and later it becomes milder and vanishes completely by the end of second month.Due to non fulfillment of dauhrida and presence of fetus, vata gets provoked and causes vomiting.Physiological changes which are naturally occurring in women leads to Dosh Utklesh .Also, the  change in lifestyle leads to Mithya Aahar Vihar which further causes various complications during pregnancy.The only description of Chardi in Garbhini is that of a lakshana, that is, Sadhyo Gruhit Garbha Lakshana. If the chardi’s lakshana falls within the normal range, it is considered Prakrut (harmless).But if it gets excessive and interferes woman’s daily activities, it is considered as a sickness that requires early intervention  to prevent complications of hyperemesis gravidarum.According to MEDLINE, PUBMED, and EMBASE lilacs, incidence of emesis gravidarum is 70%, and that of hyperemesis gravidarum is between 0.8 to 2.3%.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 35.00 Year(s)(—)
性别
Female

入选标准

  • Patients with pregnancy between 18-35 years of age.
  • All pregnant woman with chardi vega in 1st trimester of pregnancy.
  • Primi gravida with 4- 5 episodes ofvomiting.
  • Patients willing for drug administration.

排除标准

  • Patients with hyperemesis gravidarum (more than 5 episodes of vomiting with dehydration) Patients in whom chardi is seen in 2nd and 3rd trimester of pregnancy.
  • Vomiting in pregnancy associated with systemic disorders like hyperacidity, peptic disorders, hepatitis.
  • Patients of multiple pregnancy, gestational trophoblastic disease, hydatiform mole.
  • A known case of HIV, TB ,Thyroid and DM.
  • Patients with complications like severe dehydration,keto acidosis.
  • Patients with blood pressure less than 100/70 mm Hg.

结局指标

主要结局

To compare the effect of Bhunimba Sharkara vati and Bilvamajja vati in the management of garbhini chardi in first trimester w.s.r. to emesis gravidarum

时间窗: On 4th,7th,11th,15th day after drug administration

次要结局

未报告次要终点

研究者

发起方
Vd Veena Ramesh Kelamangalath
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Vd Veena Ramesh Kelamangalath

Ashvin Rural Ayurved College And Hospital

研究点 (1)

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